1: NaBH4 / ethanol / -20 - 0 °C 2: 73 percent / H2 / P-2 nickel View Scheme

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '10773376', constants.ctx, '0')">chromium(VI) oxide</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '2037554', constants.ctx, '0')">sulfuric acid</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '635680', constants.ctx, '0')">acetone</a> <br />&nbsp;1.) 0 deg C, 1 h 2.) 20 deg C, 4 h;&nbsp;&nbsp;Yield given;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 3 steps<br /> </b>1: 1.) EtMgBr 2.) CuCl / 1.) THF, reflux, 2 h 2.) THF, HMPA, 0 deg C<br />2: 3.5 M H₂SO₄ / acetone / 5 h / 25 &deg;C<br />3: CrO₃, 3.5 M H₂SO₄ / acetone / 1.) 0 deg C, 1 h 2.) 20 deg C, 4 h<br /> <br /> &nbsp;

<b>Multi-step reaction with 3 steps<br /> </b>1: 1.) EtMgBr 2.) CuCl / 1.) THF, reflux, 2 h 2.) THF, HMPA, 0 deg C<br />2: 3.5 M H₂SO₄ / acetone / 5 h / 25 &deg;C<br />3: CrO₃, 3.5 M H₂SO₄ / acetone / 1.) 0 deg C, 1 h 2.) 20 deg C, 4 h<br /> <br /> &nbsp;