[(3S,6S)-1-甲基-7-氧代-6-[[(E,2R,3R,4S,5R)-3,4,5-三羟基-2-甲氧基-8-甲基壬-6-烯酰基]氨基]氮杂环庚-3-基]十四烷酸酯合成路线 （共 31 条）
反应条件
1: 93 percent / MeONa / methanol / Ambient temperature
2: 33 percent / 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride, DMAP / CH2Cl2; tetrahydrofuran / -50 - -15 °C
3: 50 percent / TFA / tetrahydrofuran; H2O / -15 - 20 °C
View Scheme
参考文献
Chida, Noritaka; Tobe, Takahiko; Murai, Katsuyuki; Yamazaki, Kaori; Ogawa, Seiichiro
Heterocycles, 1994 , vol. 38, # 11 p. 2383 - 2388
