6-溴-2,2'-联吡啶合成路线 （共 27 条）
参考文献
Journal of the Chemical Society, , p. 1662,1669
反应条件
sodium hydride 2) HMPA, r.t., 20 min; Multistep reaction;
参考文献
Uenishi, Jun'ichi; Tanaka, Takakazu; Nishiwaki, Kenji; Wakabayashi, Shoji; Oae, Shigeru; Tsukube, Hiroshi
Journal of Organic Chemistry, 1993 , vol. 58, # 16 p. 4382 - 4388
反应条件
1: tetrakis(triphenylphosphine)palladium(0) / toluene / 72 h / 90 °C
2: HCl / 60 °C
View Scheme
参考文献
Uenishi, Jun'ichi; Tanaka, Takakazu; Nishiwaki, Kenji; Wakabayashi, Shoji; Oae, Shigeru; Tsukube, Hiroshi
Journal of Organic Chemistry, 1993 , vol. 58, # 16 p. 4382 - 4388
反应条件
copper(I) oxide; ammonia in ethylene glycol
T=110°C; P=7600.51 Torr; 24 h;
参考文献
Huang, Kuo-Wei; Chen, Tao; He, Lipeng; Gong, Dirong; Jia, Weiguo; Yao, Liangfeng
Patent: US2012/323007 A1, 2012 ;
Location in patent: Page/Page column 13 ;
反应条件
1: 1) NaH / 2) HMPA, r.t., 20 min
2: Mg-monoperoxyphthalate / methanol / 1 h / Ambient temperature
3: 1) n-BuLi / 1) Et2O, hexane, THF, -78 deg C, 2) THF, -78 deg C, 5 min
View Scheme
参考文献
Stefankiewicz, Artur R.; Walesa-Chorab, Monika; Harrowfield, Jack; Kubicki, MacIej; Hnatejko, Zbigniew; Korabik, Maria; Patroniak, Violetta
Dalton Transactions, 2013 , vol. 42, # 5 p. 1743 - 1751
反应条件
sodium hydrogencarbonate in N-methyl-acetamide; diethyl ether
参考文献
BASF Aktiengesellschaft
Patent: US5346899 A1, 1994 ;
反应条件
1: 2-bromo-6-(pyridin-2-yl)pyridine With n-butyllithium
2: N,N-dimethyl-formamide
参考文献
Slater, Jonathan W.; Steel, Peter J.
Tetrahedron Letters, 2006 , vol. 47, # 39 p. 6941 - 6943
