反应条件
1: KOH / diethyl ether / 0.5 h / 0 °C
2: LiBr / acetone / 1 h / Ambient temperature
3: 1.) EtMgBr 2.) CuCl / 1.) THF, reflux, 2 h 2.) THF, HMPA, 0 deg C
4: 3.5 M H2SO4 / acetone / 5 h / 25 °C
5: CrO3, 3.5 M H2SO4 / acetone / 1.) 0 deg C, 1 h 2.) 20 deg C, 4 h
6: NaBH4 / ethanol / -20 - 0 °C
7: 73 percent / H2 / P-2 nickel
View Scheme
参考文献
Oehlschlager, A. C.; Czyzewska, E.; Aksela, R.; Pierce, H. D.
Canadian Journal of Chemistry, 1986 , vol. 64, p. 1407 - 1413
