1.1: 83 percent / methanol / 0.5 h / 20 °C 2.1: t-BuOK / toluene / 1 h / 0 - 20 °C 2.2: 66 percent / Aliquat(R) 336; meso-tetraphenylporphyrin iron chloride; P(OMe)3 / toluene / 48 h / 40 °C View Scheme
参考文献
Aggarwal, Varinder K.; Fulton, J. Robin; Sheldon, Chris G.; De Vicente, Javier
Journal of the American Chemical Society, 2003 , vol. 125, # 20 p. 6034 - 6035
1: phenylmethylphosphonic acid,diethyl ester With 18-crown-6 ether; sodium methylate in N,N-dimethyl-formamide T=20°C; 0.0833333 h; 2: [4-cyanophenyl]methanone in N,N-dimethyl-formamide T=20 - 120°C; Horner-Emmons-Wadsworth reaction; 6 h;
参考文献
Heynekamp, Justin J.; Weber, Waylon M.; Hunsaker, Lucy A.; Gonzales, Amanda M.; Orlando, Robert A.; Deck, Lorraine M.; Vander Jagt, David L.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 24 p. 7182 - 7189
chloro-trimethyl-silane; zinc in tetrahydrofuran T=50°C; 3 h; Yield givenYields of byproduct given;
参考文献
Ishino, Yoshio; Mihara, Masatoshi; Nishihama, Shintaro; Nishiguchi, Ikuzou
Bulletin of the Chemical Society of Japan, 1998 , vol. 71, # 11 p. 2669 - 2672
