氰乙酸甲酯合成路线

参考文献

MERCK PATENT GMBH; SCHULTZ, Melanie; SCHIEMANN, Kai; STAEHLE, Wolfgang
Patent: WO2010/112124 A1, 2010 ;
Location in patent: Page/Page column 66 ;
WO 2010/112124 A1

3304-61-8乙酰基-甘氨酸对硝基苯基酯+

105-34-0氰乙酸甲酯

100-02-7对硝基苯酚+

105688-23-1

参考文献

Igglessi-Markopoulou, Olga; Sandris, Constantine
Journal of Heterocyclic Chemistry, 1985 , vol. 22, p. 1599 - 1606

109-76-21,3-丙二胺+

105-34-0氰乙酸甲酯

111233-69-3

参考文献

THE UNIVERSITY OF NEWCASTLE RESEARCH ASSOCIATES LIMITED
Patent: WO2005/49009 A1, 2005 ;
Location in patent: Page/Page column 31-32 ;
WO 2005/049009 A1

66-25-1正己醛+

105-34-0氰乙酸甲酯

111735-80-9

参考文献

Conte, Aurelia; Dehmlow, Henrietta; Grether, Uwe; Kratochwil, Nicole A.; Kuehne, Holger; Narquizian, Robert; Panousis, Constantinos; Peters, Jens-Uwe; Ricklin, Fabienne; Roever, Stephan
Patent: US2007/275987 A1, 2007 ;
Location in patent: Page/Page column 36 ;

4815-24-12-氨基-4,5-二甲基噻吩-3-羧酸乙酯+

105-34-0氰乙酸甲酯

105219-75-8

参考文献

Pech; Bohm
Pharmazie, 1989 , vol. 44, # 11 p. 790 - 791

108-24-7乙酸酐+

105-34-0氰乙酸甲酯

31295-20-2N-乙酰-β-丙氨酸甲酯

参考文献

Fusier
Annales de Chimie (Cachan, France), 1950 , vol. <12>5, p. 882,886

105-34-0氰乙酸甲酯+

93-08-32-萘乙酮

351156-65-5

参考文献

Ye, Deju; Zhang, Yu; Wang, Fei; Zheng, Mingfang; Zhang, Xu; Luo, Xiaomin; Shen, Xu; Jiang, Hualiang; Liu, Hong
Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 5 p. 1773 - 1782

817-87-8乙基叠氮基甲酸酯+

105-34-0氰乙酸甲酯

497-25-6恶唑烷-2-酮

参考文献

Huisgen,R.; Blaschke,H.
Justus Liebigs Annalen der Chemie, 1965 , vol. 686, p. 145 - 153

40018-26-61,4-二硫-2,5-二醇+

105-34-0氰乙酸甲酯

4651-81-42-氨基噻吩-3-羧酸甲酯

参考文献

Hesse, Stephanie; Perspicace, Enrico; Kirsch, Gilbert
Tetrahedron Letters, 2007 , vol. 48, # 30 p. 5261 - 5264

75-07-0乙醛+

105-34-0氰乙酸甲酯

4651-81-42-氨基噻吩-3-羧酸甲酯

参考文献

Mugnaini, Claudia; Pedani, Valentina; Casu, Angelo; Lobina, Carla; Casti, Alberto; MacCioni, Paola; Porcu, Alessandra; Giunta, Daniela; Lamponi, Stefania; Solinas, Maurizio; Dragoni, Stefania; Valoti, Massimo; Colombo, Giancarlo; Castelli, Maria Paola; Gessa, Gian Luigi; Corelli, Federico
Journal of Medicinal Chemistry, 2013 , vol. 56, # 9 p. 3620 - 3635