1: acetoacetic acid methyl ester With n-butyllithium; sodium hydride in tetrahydrofuran T=0°C; 2: dodecyl bromide in tetrahydrofuran T=0 - 20°C;
参考文献
Burnham Institute for Medical Research; The Texas A and M University System
Patent: US2009/124681 A1, 2009 ;
Location in patent: Page/Page column 11-12 ;
US 20090124681 A1
p-toluenesulfonic acid sodium salt in water Hantzsch Dihydropyridine Synthesis; 0.3 h; Microwave irradiationRefluxGreen chemistry; Reagent/catalystTime;
参考文献
Khadilkar, Bhushan M.; Madyar, Virendra R.
Organic Process Research and Development, 2001 , vol. 5, # 4 p. 452 - 455
