1,3-丙酮二羧酸二乙酯合成路线 （共 169 条）
反应条件
sodium ethanolate in ethanol 1 h; Heating;
参考文献
Balogh; Hermecz; Meszaros; et al.
Journal of Heterocyclic Chemistry, 1980 , vol. 17, # 2 p. 359 - 368
反应条件
1: 50 percent / propyl acetate / ethanol / 1.5 h / Heating 2: 60 percent / ammonia / ethanol / 2 h / Heating View Scheme
参考文献
Zupancic, Silvo; Svete, Jurij; Stanovnik, Branko
Heterocycles, 2000 , vol. 53, # 9 p. 2033 - 2042
反应条件
1: boron trifluoride diethyl etherate / dichloromethane / 0 - 20 °C 2: lithium aluminium tetrahydride / tetrahydrofuran / 0 - 20 °C View Scheme
反应条件
1: 92 percent / BF3*Et2O / CH2Cl2 / 6 h / Ambient temperature 2: 90 percent / LiAlH4 / tetrahydrofuran / 1 h / Heating 3: 100 percent / p-toluenesulphonic acid / CH2Cl2 / 4 h / 0 °C 4: 96 percent / CaCO3, HgCl2 / acetonitrile; H2O / 1 h / Ambient temperature 5: 1) Mg / 1) ether, 2) 0 deg C, 15 min 6: 90 percent / p-toluenesulphonic acid / methanol / 4 h / Heating 7: 92 percent / pyridinium chlorochromate / CH2Cl2 / 4 h / Ambient temperature View Scheme
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 22, # 1 p. 9 - 11
反应条件
sulfuric acid T=25°C; 48 h;
参考文献
Brubaker; DeRuiter; Whitmer
Journal of Medicinal Chemistry, 1986 , vol. 29, # 6 p. 1094 - 1099
反应条件
1: 62 percent / Amberlyst-15 cation-exchange resin / toluene / 10 h / Heating 2: 80 percent / aq. NaOH / ethanol / 2 h / Heating View Scheme
参考文献
Ma, Yongmin; Luo, Wei; Quinn, Peter J.; Liu, Zudong; Hider, Robert C.
Journal of Medicinal Chemistry, 2004 , vol. 47, # 25 p. 6349 - 6362
反应条件
1: 90 percent / ammonium acetate, acetic acid / benzene / 24 h / Heating 2: 96 percent / hydrogen / 10percent Pd/C / ethanol / 5 h 3: 60 percent / hydrochloric acid / 1) H2O, reflux, 15 h, 2) at 235 deg C, 5 h View Scheme
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 26, p. 341 - 343
反应条件
Erhitzen der sauren Loesung des Reaktionsprodukts;
参考文献
Robinson
Journal of the Chemical Society, 1917 , vol. 111, p. 766
反应条件
potassium tert-butylate; ammonium chloride in ammonia 2 h; Irradiation;
参考文献
Beugelmans, R.; Bois-Choussy, M.; Boudet, B.
Tetrahedron, 1982 , vol. 38, # 23 p. 3479 - 3483
反应条件
KBrO3; sulfuric acid; Ce(NO3)3 T=25 - 35°C; activation energy, dual frequency oscillating reaction; Thermodynamic data;
参考文献
Tsukada, Masao
Chemistry Letters, 1987 , p. 1537 - 1540
