Openshaw; Robinson
Journal of the Chemical Society, 1946 , p. 912,917
Journal of the Chemical Society, 1937 , p. 941,946
Full Text Show Details
Gault
Bulletin de la Societe Chimique de France, 1912 , vol. <4> 11, p. 386
1: diethyl malonate With sodium hydride in N,N-dimethyl-formamide
T=50°C; 1.5 h;
2: N-[4-(2-chloro-1-oxopropyl)phenyl]acetamide in N,N-dimethyl-formamide
T=80°C; 3 h;
3: With water in N,N-dimethyl-formamide
参考文献
Boehringer Ingelheim Pharma GmbH and Co. KG
Patent: US7230001 B1, 2007 ;
Location in patent: Page/Page column 87 ;
US 7230001 B1
1: diethyl malonate With sodium hydride in tetrahydrofuran
cooling;
2: N-(4-(2-bromopropionyl)phenyl)acetamide in tetrahydrofuran
T=20°C; 5 h; Further stages.;
