1: 29.3 percent / sulfur, morpholine / ethanol / 4 h / 60 °C 2: (C2H5)3N / benzene / 6 h / Heating View Scheme
参考文献
Kaminka, M. E.; Vorob'eva, V. Ya.; Nikitin, V. B.; Mikhlina, E. E.; Zhirnikova, M. L.; Yakhontov, L. N.
Pharmaceutical Chemistry Journal, 1987 , vol. 21, # 8 p. 568 - 570
Khimiko-Farmatsevticheskii Zhurnal, 1987 , vol. 21, # 8 p. 945 - 948
1,3,4,6,7,8-hexahydro-2H-pyrimido[1,2-a]pyrimidine in acetonitrile T=64.9°C; 1 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Subba Rao, Yarlagadda V.; De Vos, Dirk E.; Jacobs, Pierre A.
Angewandte Chemie (International Edition in English), 1997 , vol. 36, # 23 p. 2661 - 2663