2-甲基-1,2,3-三氮唑-4-甲酸甲酯合成路线 (共 14 条)
反应条件
in tetrahydrofuran; diethyl ether T=20°C; 16 h; Inert atmosphere;
参考文献
Journal of Medicinal Chemistry, , vol. 57, # 5 p. 1770 - 1776
反应条件
in tetrahydrofuran 4 h; Ambient temperature;
参考文献
Chemische Berichte, , vol. 120, p. 159 - 170
反应条件
in tetrahydrofuran 96 h; Ambient temperaturefurther temperatures; Product distribution;
参考文献
Chemische Berichte, , vol. 120, p. 159 - 170
反应条件
1: With water; sodium hydroxide in tetrahydrofuran; methanol
T=20°C; 4 h;
2: With hydrogenchloride in tetrahydrofuran; methanol; water
参考文献
Moreau, Benoiit; O'Meara, Jeff A.; Bordeleau, Josee; Garneau, Michel; Godbout, Cedrickx; Gorys, Vida; Leblanc, Melissa; Villemure, Elisia; White, Peter W.; Llinas-Brunet, Montse
Journal of Medicinal Chemistry, 2014 , vol. 57, # 5 p. 1770 - 1776