反应条件
Multi-step reaction with 7 steps 1: 40 percent / NH3 2: 93 percent / LiAlH4 / tetrahydrofuran / Heating3: 73 percent / CrO3 4: 1.) Me3SiCN, ZnI2; 2.) HCl / 1.) CH2Cl2, 20 deg C, 1 h5: pyridine6: 86 percent / Pd(OAc)2, PPh3 / bis-(2-methoxy-ethyl) ether / 1 h / Heating7: 1.) iBu2AlH; 2.) HCl / 1.) ether, -50 deg C, 30 min; 20 deg C, 30 min; 45 deg C, 30 min
参考文献
Mandai, Tadakatsu; Gotoh, Jiso; Otera, Junzo; Kawada, Mikio Chemistry Letters, 1980 , p. 313 - 314