4-N-(4-氯苯基)磺酰基-1-N-[(2S)-3-甲基-1-氧代-1-[[(2S)-1-(1,1,1-三氟-4-甲基-2-氧代戊烷-3-基)吡咯烷-2-羰基]氨基]丁烷-2-基]苯-1,4-二甲酰胺合成路线 （共 2 条）
反应条件
NMM in dichloromethane; N,N-dimethyl-formamide
参考文献
Merrell Pharmaceuticals Inc.
Patent: US5698523 A1, 1997 ;
反应条件
4-methyl-morpholine in dichloromethane; N,N-dimethyl-formamide 2.5 h; Ambient temperature; Yield given;
参考文献
Angelastro; Baugh; Bey; Burkhart; Chen; Durham; Hare; Huber; Janusz; Koehl; Marquart; Mehdi; Peet
Journal of Medicinal Chemistry, 1994 , vol. 37, # 26 p. 4538 - 4553
