2-(氯甲基)-3,5-二氧杂-1-己烯合成路线 （共 15 条）
反应条件
potassium tert-butylate in tetrahydrofuran T=-13 - 20°C; 12 h;
参考文献
Janicki, Slawomir Z.; Fairgrieve, Jennifer M.; Petillo, Peter A.
Journal of Organic Chemistry, 1998 , vol. 63, # 11 p. 3694 - 3700
反应条件
sodium hydroxide in 1,4-dioxane T=60°C; 2 h;
参考文献
Gu, Xue-Ping; Nishida, Nobuyuki; Ikeda, Isao; Okahara, Mitsuo
Journal of Organic Chemistry, 1987 , vol. 52, # 15 p. 3192 - 3196
反应条件
sodium t-butanolate T=60°C; 3 h;
参考文献
Gu, Xue-Ping; Nishida, Nobuyuki; Ikeda, Isao; Okahara, Mitsuo
Journal of Organic Chemistry, 1987 , vol. 52, # 15 p. 3192 - 3196
反应条件
sodium t-butanolate T=60°C; 3 h;
参考文献
Gu, Xue-Ping; Nishida, Nobuyuki; Ikeda, Isao; Okahara, Mitsuo
Journal of Organic Chemistry, 1987 , vol. 52, # 15 p. 3192 - 3196
反应条件
bis-triphenylphosphine-palladium(II) chloride in benzene react. mixt. washed (aq. KF); extn.of org. layer (ether); dried over MgSO4; product isolated by distn. (reduced pressure); acetonylated by chromy. (silica gel); GLC yield given;
参考文献
Bulletin of the Chemical Society of Japan, , vol. 62, # 10 p. 3383 - 3385
反应条件
bis-triphenylphosphine-palladium(II) chloride in benzene react. mixt. washed (aq. KF); extn.of org. layer (ether); dried over MgSO4; product isolated by distn. (reduced pressure); acetonylated by chromy. (silica gel);
参考文献
Kosugi; Miyajima; Nakanishi; Sano; Migita
Bulletin of the Chemical Society of Japan, 1989 , vol. 62, # 10 p. 3383 - 3385
反应条件
sodium; tert-butyl alcohol T=60°C; 3 h;
参考文献
Gu, Xue-Ping; Nishida, Nobuyuki; Ikeda, Isao; Okahara, Mitsuo
Journal of Organic Chemistry, 1987 , vol. 52, # 15 p. 3192 - 3196
反应条件
bis-triphenylphosphine-palladium(II) chloride in benzene
react. mixt. washed (aq. KF); extn.of org. layer (ether); dried over MgSO4; product isolated by distn. (reduced pressure); acetonylated by chromy. (silica gel);
参考文献
Kosugi; Miyajima; Nakanishi; Sano; Migita
Bulletin of the Chemical Society of Japan, 1989 , vol. 62, # 10 p. 3383 - 3385
反应条件
indium; ethylene dibromide in tetrahydrofuran; water
T=20°C;
参考文献
Maslak, Veselin; Tokic-Vujosevic, Zorana; Ferjancic, Zorana; Saicic, Radomir N.
Tetrahedron Letters, 2009 , vol. 50, # 48 p. 6709 - 6711
反应条件
sulfuric acid; 1,8-diazabicyclo[5.4.0]undec-7-ene; triphenylphosphine; palladium dichloride
1.) THF, reflux, 18 h; 2.) dioxan, 60 deg C, 2 h; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Gu, Xue-Ping; Okuhara, Toshio; Ikeda, Isao; Okahara, Mitsuo
Synthesis, 1988 , # 7 p. 535 - 537
