(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride in diethyl ether T=0°C; 17.5 h;

1: 1.) BuLi; 2.) MnO2 / 1.) THF, hexane, -78 degC, 30 min; 2.) CH2Cl2, 0 degC, 30 min 2: 82.5 percent / HBr / acetic acid; CH2Cl2 / 2 h / 0 °C View Scheme

water; magnesium Multistep reaction;