反应条件
Multi-step reaction with 5 steps 1.1: Mg; 1,2-dibromoethane / tetrahydrofuran / 0.5 h / Heating1.2: tetrahydrofuran / 0.5 h / 0 °C2.1: aq. H2O2; aq. NaHCO3 / methanol; tetrahydrofuran / 2.5 h / 70 °C3.1: 1.14 g / H2 / 5 percent Pd/C / ethanol / 6.5 h / 50 °C4.1: methanol / 2 h / 20 °C5.1: TEMPO; NaClO2; NaClO / aq. phosphate buffer; acetonitrile / 35 °C / pH 6.7
参考文献
Ikunaka, Masaya; Matsumoto, Jun; Nishimoto, Yukifumi Tetrahedron Asymmetry, 2002 , vol. 13, # 11 p. 1201 - 1208
