(7alpha,17alpha)-3,3-二甲氧基-7-甲基-19-去甲孕甾-5(10)-烯-20-炔-17-醇合成路线 （共 5 条）
反应条件
potassium tert-butylate in tetrahydrofuran T=0°C; 2 h;
参考文献
Van Vliet; Broess; Peters; et al.
Recueil des Travaux Chimiques des Pays Bas, 1986 , vol. 105, # 4 p. 111 - 115
反应条件
1: 86 percent / malonic acid / 24 h / 20 °C 2: 91 percent / potassium tert-butoxide / tetrahydrofuran / 2 h / 0 °C View Scheme
参考文献
Van Vliet; Broess; Peters; et al.
Recueil des Travaux Chimiques des Pays Bas, 1986 , vol. 105, # 4 p. 111 - 115
反应条件
1: 98 percent / magnesium methoxide / tetrahydrofuran; liquid ammonia / 1 h / -35 °C 2: 86 percent / malonic acid / 24 h / 20 °C 3: 91 percent / potassium tert-butoxide / tetrahydrofuran / 2 h / 0 °C View Scheme
参考文献
Van Vliet; Broess; Peters; et al.
Recueil des Travaux Chimiques des Pays Bas, 1986 , vol. 105, # 4 p. 111 - 115
反应条件
oxalic acid in ethanol; water T=20°C; 2 h; Yields of byproduct given;
参考文献
Van Vliet; Broess; Peters; et al.
Recueil des Travaux Chimiques des Pays Bas, 1986 , vol. 105, # 4 p. 111 - 115
反应条件
in water Acidic conditions; Product distribution / selectivity;
参考文献
NEWCHEM S.P.A.
Patent: WO2006/125453 A1, 2006 ;
Location in patent: Page/Page column 4-9 ;
