5-(三氟甲基)-1H-吡唑-3-羧酸合成路线 （共 5 条）
反应条件
thionyl chloride in pyridine 3 h; Heating;
参考文献
Dann, Otto; Char, Helmut; Fleischmann, Paul; Fricke, Helmut
Liebigs Annalen der Chemie, 1986 , # 3 p. 438 - 455
反应条件
1: Natriumacetate / acetic acid / Heating 2: NaOH / H2O / Heating 3: 42 percent / CH3ONa / bis-(2-hydroxy-ethyl) ether / 1 h / 150 - 160 °C 4: 97 percent / SOCl2 / pyridine / 3 h / Heating View Scheme
参考文献
Liebigs Annalen der Chemie, , # 3 p. 438 - 455
反应条件
1: NaOH / H2O / Heating 2: 42 percent / CH3ONa / bis-(2-hydroxy-ethyl) ether / 1 h / 150 - 160 °C 3: 97 percent / SOCl2 / pyridine / 3 h / Heating View Scheme
参考文献
Liebigs Annalen der Chemie, , # 3 p. 438 - 455
反应条件
in ethanol 2 h; Heating;
参考文献
Dann, Otto; Char, Helmut; Fleischmann, Paul; Fricke, Helmut
Liebigs Annalen der Chemie, 1986 , # 3 p. 438 - 455
反应条件
1: 74 percent / ethanol / 2 h / Heating
2: 48 percent / LiAlH4 / diethyl ether / 1 h / Ambient temperature
View Scheme
参考文献
Dann, Otto; Char, Helmut; Fleischmann, Paul; Fricke, Helmut
Liebigs Annalen der Chemie, 1986 , # 3 p. 438 - 455
