1: With sodium tetrahydroborate in tetrahydrofuran; methanol
T=15 - 26°C;
2: With sodium hydroxide in tetrahydrofuran; methanol; water
Product distribution / selectivity;
参考文献
ASTRAZENECA AB
Patent: WO2009/35407 A1, 2009 ;
Location in patent: Page/Page column 10; 21 ;