1-[10-[3-(4-甲基哌嗪-1-基)丙基]吩噻嗪-2-基]乙酮合成路线 （共 3 条）
反应条件
1: 1-methyl-piperazine With sodium hydride in dimethyl sulfoxide T=20°C; 1 h; 2: 3-(2-acetyl-10H-phenothiazin-10-yl)-propyl bromide in dimethyl sulfoxide T=20°C; 12 h;
参考文献
Schmidt, Matthias; Teitge, Marlen; Castillo, Marianela E.; Brandt, Tobias; Dobner, Bodo; Langner, Andreas
Archiv der Pharmazie, 2008 , vol. 341, # 10 p. 624 - 638
反应条件
sodium hydroxide in toluene 15 h; Heating;
参考文献
Grisenko,A.N.; Zhuravlev,S.V.
J. Gen. Chem. USSR (Engl. Transl.), 1962 , vol. 32, p. 1915 - 1919,1892 - 1895
反应条件
(i) TsOH, ethane-1,2-diol, toluene, (ii) NaNH2, (iii) /BRN= 106074/, (iv) aq. HCl; Multistep reaction;
参考文献
Craig,P.N. et al.
Journal of Organic Chemistry, 1961 , vol. 26, p. 1138 - 1143
