2,4,5-三氯-7H-吡咯[2,3-D]嘧啶合成路线 （共 2 条）
反应条件
N-chloro-succinimide in N,N-dimethyl-formamide T=20°C; 48 h;
参考文献
GATEKEEPER PHARMACEUTICALS, INC.; GRAY, Nathanael, S.; ZHOU, Wenjun
Patent: WO2011/140338 A1, 2011 ;
Location in patent: Page/Page column 75 ;
反应条件
Selectfluorreg;; acetic acid in acetonitrile T=60°C; 5 h;
参考文献
Helvetica Chimica Acta, , vol. 91, # 6 p. 1083 - 1105
