hydrogenchloride T=85°C; 19 h;

1: 1.) N-bromosuccinimide, HF, pyridine, 2.) t-BuOK / 1.) ether, RT, 2 h, 2.) THF, from -30 deg C to -20 deg C, 2 h 2: 33 percent / 1 N aq. HCl / 19 h / 85 °C View Scheme

1: 95 percent / 180 °C 2: 1.) N-bromosuccinimide, HF, pyridine, 2.) t-BuOK / 1.) ether, RT, 2 h, 2.) THF, from -30 deg C to -20 deg C, 2 h 3: 33 percent / 1 N aq. HCl / 19 h / 85 °C View Scheme