4-叔丁基二甲基硅烷基氧基苯乙酸甲酯合成路线 （共 2 条）
反应条件
Na3PO4*12H2O in N,N-dimethyl-formamide T=20°C; 2.5 h; chemoselective reaction;
参考文献
Synthetic Communications, , vol. 42, # 2 p. 285 - 291
反应条件
1: 99 percent / LiAlH4 / diethyl ether / 1.75 h / 20 °C
2: 3.59 g / pyridinium chlorochromate / CH2Cl2 / 5 h / 0 °C
3: 1.99 g / diethyl ether / 1 h / -78 °C
4: 83 percent / (COCl)2; DMSO; Et3N / CH2Cl2 / 2 h / -78 - -20 °C
5: 51 percent / HCl; NaBH3CN / methanol / 24 h / 20 °C
6: 83 percent / H2SO4 / methanol / 3.5 h / 20 °C
View Scheme
参考文献
Nakajima, Rika; Ono, Machiko; Aiso, Sadakazu; Akita, Hiroyuki
Chemical and Pharmaceutical Bulletin, 2005 , vol. 53, # 6 p. 684 - 687
