2-(2-氟-6-甲基氨基-吡啶-3-基)-苯并呋喃-5-醇合成路线 （共 3 条）
反应条件
boron tribromide in dichloromethane T=0 - 20°C;
参考文献
Swahn, Britt-Marie; Sandell, Johan; Pyring, David; Bergh, Margareta; Jeppsson, Fredrik; Jureus, Anders; Neelissen, Jan; Johnstroem, Peter; Schou, Magnus; Svensson, Samuel
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 13 p. 4332 - 4337
反应条件
1: bis-triphenylphosphine-palladium(II) chloride; triethylamine / ethanol / 0.25 h / 140 °C / Microwave irradiation 2: sodium hexamethyldisilazane / tetrahydrofuran / 0 - 20 °C 3: sodium hydride / N,N-dimethyl-formamide / 0 - 20 °C 4: boron tribromide / dichloromethane / 0 - 20 °C View Scheme
参考文献
Swahn, Britt-Marie; Sandell, Johan; Pyring, David; Bergh, Margareta; Jeppsson, Fredrik; Jureus, Anders; Neelissen, Jan; Johnstroem, Peter; Schou, Magnus; Svensson, Samuel
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 13 p. 4332 - 4337
反应条件
1: bis-triphenylphosphine-palladium(II) chloride; triethylamine / ethanol / 0.25 h / 140 °C / Microwave irradiation 2: sodium hexamethyldisilazane / tetrahydrofuran / 0 - 20 °C 3: sodium hydride / N,N-dimethyl-formamide / 0 - 20 °C 4: boron tribromide / dichloromethane / 0 - 20 °C View Scheme
参考文献
Swahn, Britt-Marie; Sandell, Johan; Pyring, David; Bergh, Margareta; Jeppsson, Fredrik; Jureus, Anders; Neelissen, Jan; Johnstroem, Peter; Schou, Magnus; Svensson, Samuel
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 13 p. 4332 - 4337
