boron trichloride in dichloromethane
T=-78°C; 2.5 h;
参考文献
Marquez, Victor E.; Lim, Mu-Ill; Treanor, Susan P.; Plowman, Jacqueline; Priest, Matthew A.; et al.
Journal of Medicinal Chemistry, 1988 , vol. 31, # 9 p. 1687 - 1694
Multi-step reaction with 3 steps 1: 71 percent / cuprous oxide, 1,10-phenanthroline / quinoline / 0.25 h / 170 °C2: 64 percent / Lawesson's reagent / hexamethylphosphoric acid triamide / 2.45 h / 100 °C3: 64 percent / ammonia / methanol / 18 h / 60 °C
参考文献
Marquez, Victor E.; Lim, Mu-Ill; Treanor, Susan P.; Plowman, Jacqueline; Priest, Matthew A.; et al. Journal of Medicinal Chemistry, 1988 , vol. 31, # 9 p. 1687 - 1694
Multi-step reaction with 3 steps 1: 62 percent / ammonia, ammonium hydroxide / dimethylformamide / 4 h / Ambient temperature2: 64 percent / Lawesson's reagent / hexamethylphosphoric acid triamide / 2.45 h / 100 °C3: 64 percent / ammonia / methanol / 18 h / 60 °C
参考文献
Marquez, Victor E.; Lim, Mu-Ill; Treanor, Susan P.; Plowman, Jacqueline; Priest, Matthew A.; et al. Journal of Medicinal Chemistry, 1988 , vol. 31, # 9 p. 1687 - 1694
