7-溴-1H-吡咯并[2,3-B][1,4]恶嗪-2(3H)-酮合成路线 （共 5 条）
反应条件
1: With iron; acetic acid T=60°C; 2.5 h; 2: With sodium carbonate in methanol; dichloromethane; water
参考文献
Ackermann, Jean; Bleicher, Konrad; Ceccarelli, Simona M.; Chomienne, Odile; Mattei, Patrizio; Sander, Ulrike Obst
Patent: US2007/191603 A1, 2007 ;
Location in patent: Page/Page column 37 ;
反应条件
1: With hydrogenchloride; tin(IV) chloride in water T=80°C; 1 h; 2: With sodium hydroxide in water T=20°C;
参考文献
Ahn, Sung Oh; Park, Chan Hee; Im, Jun Hwan; Lee, Soon Ok; Lee, Kyoung June; Cho, Seong Wook; Ko, Kwang Seok; Han, Sun Young; Lee, Won Il
Patent: US2011/28467 A1, 2011 ;
Location in patent: Page/Page column 52 ;
US 20110028467 A1
反应条件
1: 62 percent 2: 71.6 percent / conc. HCl/Sn / 1 h / 80 - 85 °C View Scheme
参考文献
Zeitschrift fuer Chemie (Stuttgart, Germany), , vol. 26, # 3 p. 99
反应条件
1: With borane-THF in tetrahydrofuran
T=0°C; 3 h; Heating / reflux;
2: With hydrogenchloride; water
T=100°C; 1.25 h;
3: With sodium hydroxide in water
pH=10;
参考文献
Ackermann, Jean; Bleicher, Konrad; Ceccarelli, Simona M.; Chomienne, Odile; Mattei, Patrizio; Sander, Ulrike Obst
Patent: US2007/191603 A1, 2007 ;
Location in patent: Page/Page column 37 ;
反应条件
triethylsilane; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct; triethylamine in N,N-dimethyl-formamide
T=110°C; P=3102.97 Torr; 12 h;
参考文献
Hameed P., Shahul; Shanbhag, Gajanan; Shinde, Vikas; Chinnapattu, Murugan; Manjrekar, Praveena; Puttur, Jayashree; Patil, Vikas; Ugarkar, Bheemarao
Synthetic Communications, 2013 , vol. 43, # 24 p. 3315 - 3321
