反应条件
Multi-step reaction with 6 steps 1: 73 percent / Mg / diethyl ether / 3.5 h / 23 °C2: 1.) NaIO4, 2.) LiAlH4 / 1.) 24 deg C, 1 h, aqueous acetone, 2.) THF, 20 deg C, 20 min3: 97 percent / imidazole / dimethylformamide / 2.66 h / 24 °C4: pyridinium chlorochromate, molecular sieves 3 Angstroem / CH2Cl2 / 2 h / 22 °C5: 57 percent / LiAlH4 / diethyl ether / 2 h / -78 °C6: NaH / tetrahydrofuran / 8 h / Ambient temperature
参考文献
Nakata; Arai; Tomooka; Ohsawa; Kinoshita Bulletin of the Chemical Society of Japan, 1989 , vol. 62, # 8 p. 2618 - 2635