sodium methylate in methanol 1 h;

sodium methylate in methanol 1 h;

Multi-step reaction with 3 steps 1: p-toluenesulfonic acid monohydrate / benzene / 1 h / Ambient temperature2: 1.41 g / 80percent acetic acid / 0.25 h / Ambient temperature3: 76 percent / mercuric bromide, mercuric cyanide, molecular sieves 4A / acetonitrile / Ambient temperature  

Multi-step reaction with 4 steps 1: 88 percent / trifluoroacetic acid, water / 1 h / Ambient temperature2: p-toluenesulfonic acid monohydrate / benzene / 1 h / Ambient temperature3: 1.41 g / 80percent acetic acid / 0.25 h / Ambient temperature4: 76 percent / mercuric bromide, mercuric cyanide, molecular sieves 4A / acetonitrile / Ambient temperature