反应条件
1.1: iso-propylmagnesium bromide / tetrahydrofuran / -20 °C / |Inert atmosphere 1.2: 0.25 h / -5 °C / |Inert atmosphere 2.1: 2,2,6,6-tetramethyl-1-piperidinyloxy, free radical; sodium hypochlorite; sodium bromide; sodium hydrogencarbonate / dichloromethane / 2 h / 0 °C 2.2: pH 2 - 3 View Scheme
参考文献
ZHEJIANG HISOAR PHARMACEUTICAL CO., LTD.; Pan, Xianhua; Li, Weijin; Zhang, Qunhui; Ruan, Libo; Yu, Wansheng; Deng, Fei; Ma, Tianhua; Huang, Mingwang; He, Minhuan
Patent: US2013/281695 A1, 2013 ;
