1056246-70-8合成路线 （共 32 条）
反应条件
1: 83 percent / NaBH4 / ethanol; tetrahydrofuran / 25 °C 2: 96 percent / p-toluenesulfonic acid / benzene / Heating 3: 98 percent / NiCl2<dppp>2 / diethyl ether / Heating 4: 97 percent / H2 / PtO2 / tetrahydrofuran / 1034.3 Torr View Scheme
参考文献
Adamczyk, Maciej; Watt, David S.; Netzel, Daniel A.
Journal of Organic Chemistry, 1984 , vol. 49, # 22 p. 4226 - 4237
反应条件
1: 83 percent / NaBH4 / ethanol; tetrahydrofuran / 25 °C
2: 96 percent / p-toluenesulfonic acid / benzene / Heating
3: 98 percent / NiCl2<dppp>2 / diethyl ether / Heating
View Scheme
参考文献
Adamczyk, Maciej; Watt, David S.; Netzel, Daniel A.
Journal of Organic Chemistry, 1984 , vol. 49, # 22 p. 4226 - 4237
反应条件
acetic acid
T=20°C; Reflux;
参考文献
Chang, Meng-Yang; Lee, Tein-Wei; Hsu, Ru-Ting; Yen, Tzu-Lin
Synthesis, 2011 , # 19 art. no. H56511SS, p. 3143 - 3151
参考文献
Kutscherow
Zhurnal Obshchei Khimii, 1950 , vol. 20, p. 1662,1663; engl. Ausg. S. 1725, 1726
反应条件
Cu(2,9-bis(p-anisyl)-1,10-phenanthroline)2Cl in acetonitrile
7 h; IrradiationInert atmosphere;
参考文献
Pirtsch, Michael; Paria, Suva; Matsuno, Taisuke; Isobe, Hiroyuki; Reiser, Oliver
Chemistry - A European Journal, 2012 , vol. 18, # 24 p. 7336 - 7340
反应条件
in N,N-dimethyl-formamide
T=20°C;
参考文献
Voets, Marieke; Antes, Iris; Scherer, Christiane; Mueller-Vieira, Ursula; Biemel, Klaus; Marchais-Oberwinkler, Sandrine; Hartmann, Rolf W.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 7 p. 2222 - 2231
反应条件
1: 65 percent / dimethylformamide / 20 °C
2: 91 percent / NaBH4 / methanol / 1 h / 20 °C
3: 96 percent / acetic acid; sulfuric acid / 4 h / 100 °C
View Scheme
参考文献
Voets, Marieke; Antes, Iris; Scherer, Christiane; Mueller-Vieira, Ursula; Biemel, Klaus; Marchais-Oberwinkler, Sandrine; Hartmann, Rolf W.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 7 p. 2222 - 2231
反应条件
1: 88 percent / NaBH4 / methanol; tetrahydrofuran / 0.75 h / 0 - 20 °C
2: 81 percent / p-toluenesulfonic acid / toluene / 2 h / Heating
View Scheme
参考文献
Adamczyk, Maciej; Watt, David S.; Netzel, Daniel A.
Journal of Organic Chemistry, 1984 , vol. 49, # 22 p. 4226 - 4237
反应条件
sodium methylate; sodium in methanol
参考文献
Sandoz, Inc.
Patent: US3959308 A1, 1976 ;
反应条件
hydroxylamine hydrochloride in water
参考文献
Yang, Hai-tao; Ruan, Xiao-Jiao; Miao, Chun-bao; Xi, Hai-tao; Jiang, Yan; Meng, Qi; Sun, Xiao-qiang
Tetrahedron Letters, 2009 , vol. 50, # 52 p. 7337 - 7339
