2-(2-硝基-苯基)-丙二酸二乙酯合成路线 （共 7 条）
反应条件
potassium carbonate in N,N-dimethyl-formamide T=100°C; 3 h;
参考文献
Naik, Nilesh H.; Urmode, Tukaram D.; Sikder, Arun K.; Kusurkar, Radhika S.
Australian Journal of Chemistry, 2013 , vol. 66, # 9 p. 1112 - 1114
反应条件
sodium hydride in tetrahydrofuran
参考文献
THRESHOLD PHARMACEUTICALS, INC.
Patent: WO2006/15191 A2, 2006 ;
Location in patent: Page/Page column 79 ;
反应条件
sodium hydride; copper(I) bromide in 1,4-dioxane 2 h; Heating;
参考文献
Setsune, Jun-ichiro; Matsukawa, Kimihiro; Wakemoto, Hirofumi; Kitao, Teijiro
Chemistry Letters, 1981 , p. 367 - 370
反应条件
in N,N-dimethyl-formamide T=20°C; Alkylation;
参考文献
Gurjar; Reddy; Murugaiah
Synthesis, 2000 , # 12 p. 1659 - 1661
反应条件
hydrogenchloride; water T=20°C; 12 h;
参考文献
Naik, Nilesh H.; Urmode, Tukaram D.; Sikder, Arun K.; Kusurkar, Radhika S.
Australian Journal of Chemistry, 2013 , vol. 66, # 9 p. 1112 - 1114
反应条件
magnesium chloride in N,N-dimethyl acetamide T=140 - 150°C; Decarboxylation; Krapcho's reaction; 24 h;
参考文献
Gurjar; Reddy; Murugaiah
Synthesis, 2000 , # 12 p. 1659 - 1661
反应条件
in xylene
100 h; Heating;
参考文献
Duffy, Kevin J.; Tennant, George
Journal of the Chemical Society, Chemical Communications, 1995 , # 23 p. 2457 - 2460
