6-氟-3,4-二氢-2H-苯并[1,4]恶嗪合成路线 （共 4 条）
反应条件
lithium aluminium tetrahydride in tetrahydrofuran T=0 - 20°C;
参考文献
SENEXIS LIMITED; HORWELL, David Christopher; SCOPES, David Ian Carter
Patent: WO2011/144578 A1, 2011 ;
Location in patent: Page/Page column 32; 33 ;
反应条件
potassium carbonate in N,N-dimethyl-formamide T=125°C; 15 h;
参考文献
Tetrahedron Letters, , vol. 47, # 44 p. 7823 - 7826
反应条件
1.1: potassium carbonate / acetone / 3 h / Reflux 2.1: acetic acid; iron / 20 °C 2.2: pH 7 3.1: lithium aluminium tetrahydride / tetrahydrofuran / 0 - 20 °C View Scheme
反应条件
1.1: acetic acid; iron / 20 °C 1.2: pH 7 2.1: lithium aluminium tetrahydride / tetrahydrofuran / 0 - 20 °C View Scheme
