N,N,N′,N′-四甲基-O-(N-琥珀酰亚胺)脲四氟硼酸盐合成路线 （共 16 条）
反应条件
1: oxalyl chloride 2: KBF4, HCl View Scheme
参考文献
Tetrahedron Letters, , vol. 30, # 15 p. 1927 - 1930
反应条件
hydrogenchloride; potassium tetrafluoroborate
参考文献
Tetrahedron Letters, , vol. 30, # 15 p. 1927 - 1930
反应条件
sodium hydrogencarbonate; N-ethyl-N,N-diisopropylamine in tetrahydrofuran; water
参考文献
Novo Nordisk A/S
Patent: US2012/93840 A1, 2012 ;
反应条件
N-ethyl-N,N-diisopropylamine in DMF (N,N-dimethyl-formamide) T=20°C; pH=8.3; 1 h;
参考文献
US6353124 B1, ;
Page column 7 ;
→
104211-94-1(2,5-二氧代吡咯烷-1-基)(4R)-4-[(3R,5R,10S,13R,17S)-3-羟基-10,13-二甲基-2,3,4,5,6,7,8,9,11,12,14,15,16,17-十四氢-1H-环戊二烯并[a]菲-17-基]戊酸酯
反应条件
N-ethyl-N,N-diisopropylamine in DMF (N,N-dimethyl-formamide) T=20°C; 2 h;
参考文献
Mahato, Ram I.; Maheshwari, Anurag; Kim, Sung Wan
Patent: US2005/32722 A1, 2005 ;
Location in patent: Page/Page column 4 ;
反应条件
N-ethyl-N,N-diisopropylamine in DMF (N,N-dimethyl-formamide) pH=8.5; 0.166667 h;
参考文献
US6353124 B1, ;
Page column 9 ;
反应条件
N-ethyl-N,N-diisopropylamine in 1-methyl-pyrrolidin-2-one T=20°C; 1 h;
参考文献
Clave, Guillaume; Volland, Herve; Flaender, Melanie; Gasparutto, Didier; Romieu, Anthony; Renard, Pierre-Yves
Organic and Biomolecular Chemistry, 2010 , vol. 8, # 19 p. 4329 - 4345
反应条件
N-ethyl-N,N-diisopropylamine in tetrahydrofuran T=20°C;
参考文献
Malik, Leila; Nygaard, Jesper; Hoiberg-Nielsen, Rasmus; Arleth, Lise; Hoeg-Jensen, Thomas; Jensen, Knud J.
Langmuir, 2012 , vol. 28, # 1 p. 593 - 603
反应条件
triethylamine in dimethyl sulfoxide T=20°C; 2 h; Inert atmosphere;
参考文献
Uddin, Md Jashim; Marnett, Lawrence J.
Organic Letters, 2008 , vol. 10, # 21 p. 4799 - 4801
反应条件
N-ethyl-N,N-diisopropylamine in tetrahydrofuran; water; N,N-dimethyl-formamide T=20°C; 1 h;
参考文献
Restituyo, Jose A.; Comstock, Lindsay R.; Petersen, Scott G.; Stringfellow, Thomas; Rajski, Scott R.
Organic Letters, 2003 , vol. 5, # 23 p. 4357 - 4360
