7-苄基-2,4-二氯-5,6,7,8-四氢吡啶并[3,4-D]嘧啶合成路线 （共 3 条）
反应条件
N-ethyl-N,N-diisopropylamine; trichlorophosphate in N,N-dimethyl-formamide T=0 - 130°C; 2 h;
参考文献
ZHOU, Han-Jie; PARLATI, Francesco; WUSTROW, David
Patent: WO2014/15291 A1, 2014 ;
Location in patent: Page/Page column 174; 175 ;
反应条件
1: sodium methylate / methanol / 96 h / 0 - 60 °C / |Inert atmosphere 2: trichlorophosphate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 2 h / 0 - 130 °C View Scheme
反应条件
1: 1-chloroethyl chlorocarbonate / 1,2-dichloro-ethane / 16.25 h / 0 - 20 °C 2: triethylamine / dichloromethane / 16 h / 0 - 20 °C View Scheme
参考文献
ZHOU, Han-Jie; PARLATI, Francesco; WUSTROW, David
Patent: WO2014/15291 A1, 2014 ;
