1-甲基-3-苯基-1H-吡唑-4-羧酸合成路线 （共 6 条）
反应条件
N-bromosuccinmide in acetonitrile T=70°C; 1 h;
参考文献
ELI LILLY AND COMPANY
Patent: WO2006/102194 A1, 2006 ;
Location in patent: Page/Page column 181 ;
WO 2006/102194 A1
反应条件
bromine in chloroform T=0°C; 0.166667 h;
参考文献
Kano, Kunio; Scarpetti, David; Warner, John C.; Anselme, Jean-Pierre; Springer, James H.; Arison, Byron H.
Canadian Journal of Chemistry, 1986 , vol. 64, p. 2211 - 2219
反应条件
1: pyridine; diethyl ether 2: diethyl ether 3: glacial acetic acid; bromine View Scheme
参考文献
v. Auwers; Schmidt
Chemische Berichte, 1925 , vol. 58, p. 537
反应条件
1: diethyl ether 2: glacial acetic acid; bromine View Scheme
参考文献
v. Auwers; Schmidt
Chemische Berichte, 1925 , vol. 58, p. 537
反应条件
1: NaOH-solution 2: glacial acetic acid; bromine View Scheme
参考文献
v. Auwers; Schmidt
Chemische Berichte, 1925 , vol. 58, p. 537
参考文献
v. Auwers; Schmidt
Chemische Berichte, 1925 , vol. 58, p. 537
