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结构式
乙二醇
甲醛
63148-62-9
MDI
丁酮
二甲基亚砜
碳酸氢钠
471-34-1
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乙二醇
甲醛
63148-62-9
MDI
丁酮
二甲基亚砜
碳酸氢钠
471-34-1
4-溴氯苯
合成路线
(共 741 条)
106-39-8
4-溴氯苯
+
1765-93-1
4-氟苯硼酸
→
反应条件
398-22-1
4-氯-4'-氟联苯
反应条件
palladium diacetate; triphenylphosphine-3,3',3''-trisulfonic acid trisodium salt; isopropylamine in water; acetonitrile T=80°C; Suzuki cross-coupling; 3 h;
参考文献
Dupuis, Christophe; Adiey, Kouacou; Charruault, Lise; Michelet, Veronique; Savignac, Monique; Genet, Jean-Pierre
Tetrahedron Letters, 2001 , vol. 42, # 37 p. 6523 - 6526
106-39-8
4-溴氯苯
+
119072-55-8
→
反应条件
42498-40-8
N-叔丁基-4-氯苯甲酰胺
反应条件
water; triphenylphosphine; cesium fluoride; palladium dichloride in dimethyl sulfoxide T=90°C;
参考文献
Jiang, Huanfeng; Liu, Bifu; Li, Yibiao; Wang, Azhong; Huang, Huawen
Organic Letters, 2011 , vol. 13, # 5 p. 1028 - 1031
123-75-1
四氢吡咯
+
106-39-8
4-溴氯苯
→
反应条件
4280-30-2
1-(4-氯-苯基)-吡咯烷
反应条件
copper(l) iodide; N,N-dimethylaminoacetic acid; TBPM in dimethyl sulfoxide T=25°C; 24 h; Inert atmosphere;
参考文献
Yang, Chu-Ting; Fu, Yao; Huang, Yao-Bing; Yi, Jun; Guo, Qing-Xiang; Liu, Lei
Angewandte Chemie, International Edition, 2009 , vol. 48, # 40 p. 7398 - 7401
Angewandte Chemie, 2009 , vol. 121, # 40 p. 7534 - 7537
106-39-8
4-溴氯苯
+
123-86-4
→
反应条件
42991-55-9
反应条件
potassium phosphate; Cu(Phen)(PPh3)Br; [HP(t-Bu3)]BF4; palladium diacetate in N,N-dimethyl-formamide T=110°C; 24 h; Inert atmosphere;
参考文献
Song, Bingrui; Himmler, Thomas; Goossen, Lukas J.
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 10 p. 1688 - 1694
106-39-8
4-溴氯苯
+
122-39-4
→
反应条件
4316-56-7
反应条件
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; palladium 10 on activated carbon; sodium t-butanolate in 1,3,5-trimethyl-benzene 24 h; Inert atmosphereReflux;
参考文献
Monguchi, Yasunari; Kitamoto, Katsunori; Ikawa, Takashi; Maegawa, Tomohiro; Sajiki, Hironao
Advanced Synthesis and Catalysis, 2008 , vol. 350, # 17 p. 2767 - 2777
106-39-8
4-溴氯苯
+
122-39-4
→
反应条件
4316-56-7
+
106336-13-4
反应条件
potassium hydroxide; PEGDM-400 in toluene T=143 - 145°C; 8 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Sukata, Kazuaki; Akagawa, Takao
Journal of Organic Chemistry, 1989 , vol. 54, # 6 p. 1476 - 1479
106-39-8
4-溴氯苯
+
76-05-1
→
反应条件
72487-06-0
反应条件
(i) Mg, (ii) /BRN= 742035/, Et2O, (iii) LiAlH4; Multistep reaction;
参考文献
Stewart,R.; Lee,D.G.
Canadian Journal of Chemistry, 1964 , vol. 42, p. 439 - 446
106-39-8
4-溴氯苯
+
201230-82-2
→
反应条件
456-21-3
反应条件
potassium fluoride; [PdBr2(PPh3)2]; triphenylphosphine in N,N-dimethyl-formamide T=110°C; 3 h;
参考文献
Okano, Tamon; Harada, Nobuyuki; Kiji, Jitsuo
Bulletin of the Chemical Society of Japan, 1992 , vol. 65, # 6 p. 1741 - 1743
106-39-8
4-溴氯苯
+
395-01-7
→
反应条件
43141-66-8
反应条件
1: With tripotassium phosphate monohydrate; C28H41ClNPPd in toluene T=100°C; 30 h; Sealed tube; 2: With water; potassium hydroxide in toluene T=100°C; 2 h; Sealed tube;
参考文献
Ge, Shaozhong; Chaladaj, Wojciech; Hartwig, John F.
Journal of the American Chemical Society, 2014 , vol. 136, # 11 p. 4149 - 4152
106-39-8
4-溴氯苯
+
89-98-5
→
反应条件
43171-49-9
反应条件
magnesium
参考文献
Rohm and Haas Company
Patent: US4225723 A1, 1980 ;
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