1.1: toluene-4-sulfonic acid / chlorobenzene; water / 5 h / 100 °C
2.1: sodium nitrite; sulfuric acid / water / 0 °C
2.2: 80 °C / Cooling with ice
3.1: hydrogenchloride; sodium hypochlorite / isopropyl alcohol; water / 0.08 h / 20 °C
View Scheme
参考文献
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM); UNIVERSITE DE NANTES; CHU NANTES; GESTIN, Jean-Francois; GUERARD, Francois; FAIVRE-CHAUVET, Alain
Patent: WO2011/95517 A1, 2011 ;
Van Belzen, Ruud; Klein, Rene A.; Smeets, Wilberth J.J.; Spek, Anthony L.; Benedix, Roland; Elsevier, Cornelis J.
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