4,4-二乙氧基-1-丁烯合成路线 （共 21 条）
反应条件
potassium permanganate; sodium disulfite in water
参考文献
Camps Bres, Flora; Guerard-Helaine, Christine; Fernandes, Carlos; Castillo, Jose A.; Lemaire, Marielle
Tetrahedron Asymmetry, 2013 , vol. 24, # 18 p. 1175 - 1181
参考文献
Makin,S.M.; Kruptsov,B.K.
J. Gen. Chem. USSR (Engl. Transl.), 1960 , vol. 30, # 10 p. 3276 - 3280,3246 - 3250
反应条件
hydrogen; Lindlar's catalyst
参考文献
Makin,S.M.; Kruptsov,B.K.
J. Gen. Chem. USSR (Engl. Transl.), 1960 , vol. 30, # 10 p. 3276 - 3280,3246 - 3250
反应条件
[rhodium(I)(carbonyl)2(acetylacetonate)]; bis-organophosphite ligand (1); hydrogen in tetrahydrofuran T=60°C; P=3102.9 Torr; 18 h; Yield given;
参考文献
Cuny, Gregory D.; Buchwald, Stephen L.
Journal of the American Chemical Society, 1993 , vol. 115, # 5 p. 2066 - 2068
反应条件
1: di-μ-chloro-bis(η4-1,5-cyclooctadiene)diiridium; methyl(diphenyl)-phosphine / dichloromethane / 24 h / 20 °C / |Inert atmosphere 2: methoxylamine hydrochloride; n-butyllithium / tetrahydrofuran; hexane / 12 h / -78 - 60 °C / |Inert atmosphere; |Cooling with acetone-dry ice View Scheme
参考文献
Journal of the American Chemical Society, , vol. 134, # 40 p. 16449 - 16451,3
反应条件
1: Br2 / 0 °C
2: 63 percent / NaNH2/Fe(NO3)3/NH3(l) / 2 h / -70 °C
3: 68 percent / EtMgBr / tetrahydrofuran / 10 h / 60 °C
4: 87 percent / LiAlH4 / tetrahydrofuran / 2.5 h / 60 °C
View Scheme
参考文献
Raifel'd, Yu. E.; Kusikova, I. P.; Zil'berg, L. L.; Arshava, B. M.; Limanova, O. V.; Makin, S. M.
Journal of Organic Chemistry USSR (English Translation), 1981 , p. 1425 - 1429
Zhurnal Organicheskoi Khimii, 1981 , vol. 17, # 8 p. 1605 - 1609
反应条件
hydrogenchloride
T=5 - 10°C; 5 h;
参考文献
Braun, Alain; Cho, Ii Hwan; Ciblat, Stephane; Clyne, Dean; Forgione, Pat; Hart, Amy C.; Huang, Guoxiang; Kim, Jungchul; Modolo, Isabelle; Paquette, Leo A.; Peng, Xiaowen; Pichlmair, Stefan; Stewart, Catherine A.; Wang, Jizhou; Zuev, Dmitry
Collection of Czechoslovak Chemical Communications, 2009 , vol. 74, # 5 p. 651 - 769
反应条件
lithium boron tetrafluoride; water in acetonitrile
24 h; Title compound not separated from byproducts;
参考文献
Latxague; Gardrat
Synthetic Communications, 1999 , vol. 29, # 10 p. 1627 - 1637
反应条件
Yield givenYields of byproduct given;
参考文献
Latxague; Gardrat
Synthetic Communications, 1999 , vol. 29, # 10 p. 1627 - 1637
反应条件
1.1: ozone / dichloromethane / -78 °C
1.2: 100 h / 20 °C / Inert atmosphere
2.1: sodium hydroxide / ethanol; water / 1 h / 0 °C / Inert atmosphere
2.2: Inert atmosphere
View Scheme
参考文献
Chen, Jingbo; Chen, Jingchao; Xie, Yan; Zhang, Hongbin
Angewandte Chemie - International Edition, 2012 , vol. 51, # 4 p. 1024 - 1027
