8-氯-5,6,7,8-四氢喹啉合成路线 （共 3 条）
反应条件
sodium hydrogencarbonate
参考文献
Roussel Uclaf
Patent: US4816465 A1, 1989 ;
反应条件
triethylamine; trichlorophosphate in dichloromethane Chlorination; reduction; 0.25 h;
参考文献
Jacobs, Christoph; Frotscher, Martin; Dannhardt, Gerd; Hartmann, Rolf W.
Journal of Medicinal Chemistry, 2000 , vol. 43, # 9 p. 1841 - 1851
反应条件
1: 100 percent / H2O2 / acetic acid / 1 h / 70 - 80 °C 2: POCl3; Et3N / CH2Cl2 / 0.25 h View Scheme
参考文献
Jacobs, Christoph; Frotscher, Martin; Dannhardt, Gerd; Hartmann, Rolf W.
Journal of Medicinal Chemistry, 2000 , vol. 43, # 9 p. 1841 - 1851
