3-乙酰基-1-甲苯磺酰基吡咯合成路线 （共 11 条）
反应条件
AlCl3, aluminium chloride in dichloromethane T=20°C; Friedel-Crafts acylation; 2 h;
参考文献
Serra Moreno, Judith; Agas, Dimitrios; Sabbieti, Maria Giovanna; Di Magno, Matteo; Migliorini, Antonella; Loreto, M. Antonietta
European Journal of Medicinal Chemistry, 2012 , vol. 57, p. 391 - 397
反应条件
acetic anhydride; aluminium trichloride in dichloromethane
参考文献
Nippon Oil Co., Ltd.
Patent: US5059694 A1, 1991 ;
反应条件
aluminium trichloride in 1,2-dichloro-ethane T=0 - 20°C; Friedel-Crafts reaction; 2 h;
参考文献
Huffman, John W.; Smith, Valerie J.; Padgett, Lea W.
Tetrahedron, 2008 , vol. 64, # 9 p. 2104 - 2112
反应条件
aluminium trichloride
参考文献
Heterocycles, , vol. 31, # 4 p. 683 - 690
反应条件
ethylaluminum dichloride in 1,2-dichloro-ethane T=0°C; Friedel-Crafts reaction; 2 h;
参考文献
Tetrahedron, , vol. 64, # 9 p. 2104 - 2112
反应条件
1: 1) tBuOK / 1) DMF, room temperature, 1h, 2) room temperature 2: 1) AlCl3 / 1) CH2Cl2, room temperature, 30 min, 2) CH2Cl2 View Scheme
参考文献
Synthetic Communications, , vol. 26, # 7 p. 1289 - 1304
反应条件
1: 90 percent / trimethylorthoformate, Tl(NO3)3*3H2O, K-10 montmorillonite / 20 °C 2: 80 percent / NaOH / methanol / Heating View Scheme
参考文献
Serra Moreno, Judith; Agas, Dimitrios; Sabbieti, Maria Giovanna; Di Magno, Matteo; Migliorini, Antonella; Loreto, M. Antonietta
European Journal of Medicinal Chemistry, 2012 , vol. 57, p. 391 - 397
反应条件
sodium tetrahydroborate; isopropyl alcohol in 1,4-dioxane 6.5 h; Heating;
参考文献
Journal of Organic Chemistry, , vol. 58, # 27 p. 7899 - 7902
反应条件
sodium hydroxide; bromine in 1,4-dioxane; water T=10°C; 0.5 h;
参考文献
Heterocycles, , vol. 60, # 10 p. 2315 - 2321
反应条件
in methanol; chloroform; Calcium chloride
参考文献
Nippon Oil Co., Ltd.
Patent: US5059694 A1, 1991 ;
