1-溴甲基-3-甲氧基-5-甲基-苯合成路线 （共 12 条）
反应条件
N-bromosuccinmide; dibenzoyl peroxide in tetrachloromethane 1 h; Heating;
参考文献
Srikrishna; Ravikumar
Synthesis, 2007 , # 1 p. 65 - 74
反应条件
N-bromosuccinmide; 2,2'-azo-bisisobutyronitrile in tetrachloromethane Bromination; 1 h; Heatingirradiation;
参考文献
Rogers, Daniel H.; Frey, Barbara; Roden, Francis S.; Russkamp, Friedrich-Wilhelm; Willis, Anthony C.; Mander, Lewis N.
Australian Journal of Chemistry, 1999 , vol. 52, # 11 p. 1093 - 1108
反应条件
N-bromosuccinmide in tetrachloromethane
参考文献
Ackermann, Jean; Alig, Leo; Chucholowski, Alexander; Groebke, Katrin; Hilpert, Kurt; Kuehne, Holger; Obst, Ulrike; Weber, Lutz; Wessel, Hans P.
Patent: US2001/1799 A1, 2001 ;
US 20010001799 A1
反应条件
N-bromosuccinmide; dibenzoyl peroxide in tetrachloromethane Bromination; 14 h; Heatingirradiation;
参考文献
Gilat, Sylvain L.; Adronov, Alex; Frechet, Jean M. J.
Journal of Organic Chemistry, 1999 , vol. 64, # 20 p. 7474 - 7484
反应条件
1.1: 80 percent / nBuLi; I2 / hexane / -78 °C 2.1: 95 percent / (COCl)2; DMSO 3.1: tBuLi / diethyl ether / -78 °C 3.2: 100 percent / diethyl ether / -78 °C 4.1: 80 percent / PCC / CH2Cl2 5.1: 53 percent / NaOAc / PdCl2(PPh3)2 / N,N-dimethyl-acetamide / 0.02 h / 140 °C / microwave irradiation View Scheme
参考文献
Koyama, Hiroya; Kamikawa, Tadao
Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 2 p. 203 - 209
反应条件
sodium hydrogencarbonate in water; acetone 4 h; Reflux;
参考文献
Tibrewal, Nidhi; Downey, Theresa E.; Van Lanen, Steven G.; Ul Sharif, Ehesan; O'Doherty, George A.; Rohr, Juergen
Journal of the American Chemical Society, 2012 , vol. 134, # 30 p. 12402 - 12405
反应条件
1: K2CO3 / dioxane 2: 67 percent / n-BuLi; I2 / -78 °C View Scheme
参考文献
Qabaja, Ghassan; M. Perchellet, Elisabeth; Perchellet, Jean-Pierre; Jones, Graham B.
Tetrahedron Letters, 2000 , vol. 41, # 17 p. 3007 - 3010
反应条件
formaldehyd; 1,3,5,7-tetra-azatricyclo[5.1.1.13,5]decane in ethanol; water
12 h; Heating;
参考文献
Paisdor, Bernd; Gruetzmacher, Hans-Friedrich; Kuck, Dietmar
Chemische Berichte, 1988 , vol. 121, p. 1307 - 1314
参考文献
Ackermann, Jean; Alig, Leo; Chucholowski, Alexander; Groebke, Katrin; Hilpert, Kurt; Kuehne, Holger; Obst, Ulrike; Weber, Lutz; Wessel, Hans P.
Patent: US2001/1799 A1, 2001 ;
US 20010001799 A1
反应条件
1: 80 percent / NaHCO3; water / acetone / 5 h / Heating
2: 94 percent / pyridinium chlorochromate; silica gel / CH2Cl2 / 0.25 h / 20 °C
3: 91 percent / diethyl ether / 0 - 20 °C
4: 93 percent / pyridinium chlorochromate / CH2Cl2 / 1 h / 20 °C
View Scheme
参考文献
Srikrishna; Ravikumar
Synthesis, 2007 , # 1 p. 65 - 74
