4-三氟甲基-5-噻唑甲酸乙酯合成路线 （共 3 条）
反应条件
sodium tetrahydroborate in N,N-dimethyl-formamide T=0°C; 0.333333 h; exothermic reaction;
参考文献
Lee, Len F.; Schleppnik, Francis M.; Howe, Robert K.
Journal of Heterocyclic Chemistry, 1985 , vol. 22, p. 1621 - 1630
反应条件
1: 55 percent / chlorobenzene / 2 h / 135 °C 2: 92 percent / POCl3 / Heating 3: 31 percent / NaBH4 / dimethylformamide / 0.33 h / 0 °C / exothermic reaction View Scheme
参考文献
Lee, Len F.; Schleppnik, Francis M.; Howe, Robert K.
Journal of Heterocyclic Chemistry, 1985 , vol. 22, p. 1621 - 1630
反应条件
1: 92 percent / POCl3 / Heating 2: 31 percent / NaBH4 / dimethylformamide / 0.33 h / 0 °C / exothermic reaction View Scheme
参考文献
Lee, Len F.; Schleppnik, Francis M.; Howe, Robert K.
Journal of Heterocyclic Chemistry, 1985 , vol. 22, p. 1621 - 1630
