1: bis(trichloromethyl) carbonate; 4-(4-morpholino-1-(1-(pyridin-3-ylmethyl)piperidin-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl)aniline hydrochloride With triethylamine in dichloromethane T=20°C; 0.0833333 h; 2: methanol in dichloromethane T=20°C;