4-哌嗪-1-噻吩并[3,2-c]吡啶合成路线 (共 3 条)
反应条件
1: 5 h; RefluxIndustry scale; 2: With hydrogenchloride in water Industry scale; 3: With sodium hydroxide in water Industry scale;
参考文献
US2010/94005 A1, ;
Page/Page column 2 ;
反应条件
sodium hydroxide in water; 2-methyl cyclohexane
反应条件
1: 85 percent / POCl3 / 2.5 h / Heating 2: 54 percent / ethanol / 24 h / 120 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 32, # 6 p. 1147 - 1156