(4-三氟甲基苯甲酰基)乙酸乙酯合成路线 （共 9 条）
反应条件
manganese(IV) oxide in dichloromethane T=20°C;
参考文献
Chemistry - An Asian Journal, , vol. 6, # 8 p. 2073 - 2079
反应条件
niobium pentachloride in dichloromethane T=20°C; 48 h; Inert atmosphere;
参考文献
Journal of Medicinal Chemistry, , vol. 55, # 5 p. 1831 - 1843
反应条件
1: ammonium chloride; zinc 2: manganese(IV) oxide / dichloromethane / 20 °C View Scheme
参考文献
Chemistry - An Asian Journal, , vol. 6, # 8 p. 2073 - 2079
反应条件
potassium tert-butylate in diethyl ether T=0 - 20°C; 10.5 h;
参考文献
Organometallics, , vol. 31, # 3 p. 966 - 975
参考文献
US2012/277224 A1, ;
Page/Page column 28 ;
US 20120277224 A1
反应条件
1: α,α,α-Trifluoro-p-toluic acid With 1,1'-carbonyldiimidazole in tetrahydrofuran Acylation; 2: malonic acid ethyl ester monopotassium salt With magnesium chloride in tetrahydrofuran Substitution; decarboxylation;
参考文献
Bioorganic and Medicinal Chemistry, , vol. 7, # 6 p. 991 - 1002
反应条件
triethylamine; magnesium chloride in acetonitrile
参考文献
Tetrahedron Letters, , vol. 43, # 7 p. 1161 - 1164
反应条件
1: 4-(N,N-dimethlyamino)pyridine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 20 °C 2: 5 h / Reflux View Scheme
参考文献
US2012/277224 A1, ;
US 20120277224 A1
