2-氧代哌啶-1-羧酸苄酯合成路线 （共 14 条）
反应条件
1: NaBH4 / methanol / 0.25 h / 0 °C
2: 5.34 g / H2SO4 / tetrahydrofuran / 1 h / 20 °C
View Scheme
参考文献
De Simone, Filippo; Saget, Tanguy; Benfatti, Fides; Almeida, Sofia; Waser, Jerome
Chemistry - A European Journal, 2011 , vol. 17, # 51 p. 14527 - 14538
反应条件
1: NaBH4 / methanol / 0.25 h / 0 °C
2: 5.34 g / H2SO4 / tetrahydrofuran / 1 h / 20 °C
3: 76 percent / oxone(R); K2CO3 / H2O; acetone / 2 h / 20 °C
4: 88 percent / DMAP; Et3N / 2 h / 20 °C
View Scheme
参考文献
Takeuchi, Yasuo; Azuma, Kumiko; Abe, Hitoshi; Sasaki, Kenji; Harayama, Takashi
Chemical and pharmaceutical bulletin, 2002 , vol. 50, # 7 p. 1011 - 1012
反应条件
magnesium
1.) THF, 2.) -78 deg C; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Giovannini, Arianna; Savoia, Diego; Umani-Ronchi, Achille
Journal of Organic Chemistry, 1989 , vol. 54, # 1 p. 228 - 234
反应条件
in tetrahydrofuran
T=-78°C; 3 h;
参考文献
Giovannini, Arianna; Savoia, Diego; Umani-Ronchi, Achille
Journal of Organic Chemistry, 1989 , vol. 54, # 1 p. 228 - 234
