2-氨基-4-三氟甲基吡啶合成路线 （共 13 条）
反应条件
1: 72 percent / H2SO4, NaNO2 / H2O / 1 h / 70 °C 2: 67 percent / Lawesson's reagent / toluene View Scheme
参考文献
Dunn
Journal of Fluorine Chemistry, 1999 , vol. 93, # 2 p. 153 - 157
反应条件
pyridine in dichloromethane
0.5 h;
参考文献
BAYER PHARMACEUTICALS CORPORATION
Patent: WO2007/64931 A2, 2007 ;
Location in patent: Page/Page column 172 ;
反应条件
1,3-Dichloro-5,5-dimethyl-2,4-imidazolidinedione in N,N-dimethyl-formamide
T=20°C; 2 h;
参考文献
Sunesis Pharmaceuticals, Inc
Patent: US2009/5359 A1, 2009 ;
Location in patent: Page/Page column 33 ;
US 20090005359 A1
