反应条件
1: hydrogenchloride / 1,4-dioxane / 54 h / 20 - 50 °C 2: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 21 h / 20 °C 3: trichlorophosphate / 2 h / 20 °C / Inert atmosphere 4: hydrogenchloride; water / tetrahydrofuran / 24 h / 60 °C View Scheme
参考文献
AMGEN INC.; BISWAS, Kaustav; BROWN, James; CHEN, Jian, J.; GORE, Vijay, Keshav; HARRIED, Scott; HORNE, Daniel, B.; KALLER, Matthew, R.; LIU, Qingyian; MA, Vu, Van; MONENSCHEIN, Holger; NGUYEN, Thomas, T.; YUAN, Chester, Chenguang; ZHONG, Wenge; ST. JEAN, David, J., Jr.
Patent: WO2012/177893 A2, 2012 ;
WO 2012/177893 A2
