2-(2-氰基乙基氨基)-2-甲基丙酸合成路线

参考文献

Li, Hui; Hong, Yufeng; Nukui, Seiji; Lou, Jihong; Johnson, Sarah; Scales, Stephanie; Botrous, Iriny; Tompkins, Eileen; Yin, Chunfeng; Zhou, Ru; He, Mingying; Jensen, Jordan; Bouzida, Djamal; Alton, Gordon; Lafontaine, Jennifer; Grant, Stephan
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 1 p. 584 - 587

106556-63-22-(2-氰基乙基氨基)-2-甲基丙酸

398491-61-73-氨基-6,6-二甲基吡咯并[3,4-C]吡唑-5(1H,4H,6H)-甲酸叔丁酯

参考文献

WO2013/91773 A1, ;

106556-63-22-(2-氰基乙基氨基)-2-甲基丙酸

106556-66-52,2-二甲基-3-羰基-吡咯啉-1-羧酸乙酯

参考文献

Patjens, Jan; Ghaffari-Tabrizi, Ramin; Margaretha, Paul
Helvetica Chimica Acta, 1986 , vol. 69, p. 905 - 907

106556-63-22-(2-氰基乙基氨基)-2-甲基丙酸

718632-46-33-氨基-6,6-二甲基- 吡咯并[3,4-c]吡唑-2,5(4H,6H)-二羧酸 5-(1,1-二甲基乙基) 2-乙酯

参考文献

Guo, Chuangxing; McAlpine, Indrawan; Zhang, Junhu; Knighton, Daniel D.; Kephart, Susan; Johnson, M. Catherine; Li, Haitao; Bouzida, Djamal; Yang, Anle; Dong, Liming; Marakovits, Joseph; Tikhe, Jayashree; Richardson, Paul; Guo, Lisa C.; Kania, Robert; Edwards, Martin P.; Kraynov, Eugenia; Christensen, James; Piraino, Joseph; Lee, Joseph; Dagostino, Eleanor; Del-Carmen, Christine; Deng, Ya-Li; Smeal, Tod; Murray, Brion W.
Journal of Medicinal Chemistry, 2012 , vol. 55, # 10 p. 4728 - 4739

106556-63-22-(2-氰基乙基氨基)-2-甲基丙酸

718632-47-43-氨基-4,6-二氢-6,6-二甲基-吡咯并[3,4-c]吡唑-1,5-二甲酸 5-叔丁基 1-乙基酯

参考文献

Guo, Chuangxing; McAlpine, Indrawan; Zhang, Junhu; Knighton, Daniel D.; Kephart, Susan; Johnson, M. Catherine; Li, Haitao; Bouzida, Djamal; Yang, Anle; Dong, Liming; Marakovits, Joseph; Tikhe, Jayashree; Richardson, Paul; Guo, Lisa C.; Kania, Robert; Edwards, Martin P.; Kraynov, Eugenia; Christensen, James; Piraino, Joseph; Lee, Joseph; Dagostino, Eleanor; Del-Carmen, Christine; Deng, Ya-Li; Smeal, Tod; Murray, Brion W.
Journal of Medicinal Chemistry, 2012 , vol. 55, # 10 p. 4728 - 4739