7-氨基-4-甲基-3-香豆素醋酸合成路线 (共 4 条)
反应条件
1: 89 percent / ethyl acetate / Heating 2: 2.) 75percent aq. H2SO4 / 2.) 25 deg C 3: 1.) KOH, 2.) H2SO4, AcOH / 1.) MeOH, reflux, 2.) reflux View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 8, # 7 p. 881 - 884
反应条件
cysteinyl-aspartyl-specific protease 3 T=37°C; pH=7.5; aq. bufferEnzymatic reaction; Kinetics;
参考文献
Angewandte Chemie, International Edition, , vol. 48, # 34 p. 6346 - 6349
Angewandte Chemie, , vol. 121, # 34 p. 6464 - 6467
反应条件
potassium hydroxide; sulfuric acid; acetic acid 1.) MeOH, reflux, 2.) reflux; Yield given. Multistep reaction;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 8, # 7 p. 881 - 884
反应条件
1: 2.) 75percent aq. H2SO4 / 2.) 25 deg C 2: 1.) KOH, 2.) H2SO4, AcOH / 1.) MeOH, reflux, 2.) reflux View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 8, # 7 p. 881 - 884